Voltaren: Advanced Topical Relief for Musculoskeletal Pain
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Voltaren (diclofenac sodium) represents a significant advancement in targeted pain management, offering prescription-strength relief through a sophisticated topical delivery system. As a nonsteroidal anti-inflammatory drug (NSAID) available in gel, cream, and solution formulations, Voltaren provides localized treatment for osteoarthritis pain and acute musculoskeletal conditions. Its innovative formulation allows for effective drug penetration while minimizing systemic exposure, making it a preferred choice among healthcare professionals for patients requiring NSAID therapy with reduced gastrointestinal risks. This product card provides comprehensive medical information for appropriate clinical use.
Features
- Contains diclofenac sodium 1% as the active pharmaceutical ingredient
- Available in gel, cream, and topical solution formulations
- Patented carrier technology ensuring optimal dermal penetration
- Alcohol-free formulation in select variants for sensitive skin
- pH-balanced to match skin’s natural acidity (approximately 5.5)
- Rapid-drying, non-greasy texture for comfortable application
- Preservative system maintaining product stability for 6 months after opening
- Multiple dosage strengths: 100g and 150g tubes with precise dosing guides
Benefits
- Provides targeted relief from osteoarthritis pain in joints amenable to topical treatment
- Reduces local inflammation at the site of application without significant systemic absorption
- Minimizes gastrointestinal complications associated with oral NSAIDs
- Offers convenient application with demonstrated efficacy in clinical trials
- Allows for combination therapy with other analgesics when medically appropriate
- Maintains therapeutic drug levels in synovial fluid for sustained pain relief
Common use
Voltaren topical formulations are primarily indicated for the treatment of osteoarthritis pain in joints amenable to topical treatment, such as the knees, hands, and elbows. The medication is also commonly prescribed for acute pain due to minor strains, sprains, and contusions. Clinical studies have demonstrated its effectiveness in reducing pain and improving physical function in patients with localized inflammatory conditions. Healthcare providers may recommend Voltaren as monotherapy or as part of a comprehensive pain management strategy, particularly for patients who cannot tolerate oral NSAIDs or who require targeted therapy.
Dosage and direction
For osteoarthritis pain: Apply 4 grams of gel to the affected foot, knee, or ankle four times daily, or 2 grams to the affected hand or elbow four times daily. The total daily dose should not exceed 16 grams for lower extremities or 8 grams for upper extremities. For the 1% topical solution, apply 40 drops to each affected knee four times daily, or 20 drops to each affected hand, elbow, or wrist four times daily. Gently massage into the skin until fully absorbed. Wash hands thoroughly after application unless treating hands. Do not apply to open wounds, damaged skin, or under occlusive dressings. Treatment duration should be periodically reevaluated based on therapeutic response.
Precautions
Avoid contact with eyes, mucous membranes, and non-intact skin. Do not apply to areas affected by dermatitis, eczema, or other skin conditions. Use with caution in patients with hepatic impairment, renal impairment, or dehydration. Monitor for skin reactions at the application site; discontinue if severe dermatitis occurs. Patients with aspirin-sensitive asthma may be at increased risk of bronchospasm. Long-term use requires periodic monitoring of renal and hepatic function. Sun exposure should be minimized on treated areas due to potential photosensitivity. Elderly patients may require closer monitoring due to increased susceptibility to NSAID adverse effects.
Contraindications
Hypersensitivity to diclofenac, aspirin, or other NSAIDs. History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Treatment perioperatively for coronary artery bypass graft (CABG) surgery. Third trimester of pregnancy. Application to compromised skin or open wounds. Concurrent use with other topical products without medical supervision. Severe renal impairment (creatinine clearance <30 mL/min). Severe hepatic impairment (Child-Pugh Class C). History of gastrointestinal bleeding or perforation with previous NSAID therapy.
Possible side effects
Most common (≥1%): Application site reactions including dryness, redness, itching, and scaling. Less common: Gastrointestinal discomfort, nausea, headache. Rare but serious: Severe skin reactions (exfoliative dermatitis, Stevens-Johnson syndrome), systemic NSAID effects including gastrointestinal ulceration/bleeding, renal impairment, hepatic injury, cardiovascular thrombotic events. Hypersensitivity reactions including anaphylaxis, bronchospasm, and angioedema. Laboratory abnormalities including elevated liver enzymes, decreased hemoglobin, and electrolyte imbalances. Long-term use may increase risk of myocardial infarction and stroke.
Drug interactions
Concomitant use with oral NSAIDs may increase risk of adverse effects. May increase lithium, digoxin, and methotrexate levels. Enhanced anticoagulant effect with warfarin and similar agents. Reduced antihypertensive effect of ACE inhibitors, angiotensin II receptor blockers, and diuretics. Increased risk of renal impairment with cyclosporine and tacrolimus. Potential interaction with other topical medications. Concomitant corticosteroids may increase gastrointestinal risk. SSRIs may increase bleeding risk. Phenytoin levels may be affected.
Missed dose
If a dose is missed, apply as soon as remembered unless it is nearly time for the next scheduled dose. Do not double the dose to make up for a missed application. Maintain regular application intervals for consistent therapeutic effect. If multiple doses are missed, contact healthcare provider for guidance on resuming therapy. The topical nature of this medication allows for more flexibility than systemic formulations, but consistent application optimizes therapeutic outcomes.
Overdose
Topical overdose is unlikely due to limited systemic absorption. However, excessive application could potentially lead to systemic NSAID toxicity. Symptoms may include headache, nausea, vomiting, epigastric pain, gastrointestinal bleeding, dizziness, drowsiness, tinnitus, or metabolic acidosis. In case of accidental ingestion, seek immediate medical attention. Treatment is supportive and symptomatic. Gastric lavage may be considered if ingestion occurred within 4 hours. Activated charcoal may be administered. Hemodialysis is not effective due to high protein binding.
Storage
Store at room temperature (20-25°C or 68-77°F). Keep tube tightly closed when not in use. Protect from excessive heat and direct sunlight. Do not freeze. Keep out of reach of children and pets. Discard any unused product 6 months after opening. Do not transfer to other containers. Check expiration date before use. Do not use if discoloration or separation occurs. Store away from heat sources and open flames.
Disclaimer
This information is for educational purposes only and does not replace professional medical advice. Always consult with a qualified healthcare provider before starting any new medication. The prescribing physician should be aware of the patient’s complete medical history and current medications. Individual results may vary. Proper diagnosis and treatment monitoring are essential for safe and effective use. This product is available by prescription only and should be used strictly as directed by a healthcare professional.
Reviews
Clinical studies demonstrate that 60-70% of patients experience significant pain reduction within 2 weeks of regular use. In a 12-week randomized controlled trial, Voltaren gel showed statistically significant improvement in WOMAC pain subscale scores compared to placebo (p<0.001). Dermatological assessments indicate good local tolerability with most reactions being mild and self-limiting. Patient satisfaction surveys report high rates of continued use due to convenience and reduced systemic side effects compared to oral NSAIDs. Healthcare providers note particular benefit for elderly patients and those with gastrointestinal contraindications to oral NSAIDs.