Rogaine 5: Clinically Proven Hair Regrowth Treatment

Product dosage: 60ml
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Synonyms

Rogaine 5 (minoxidil topical solution 5%) is an FDA-approved topical treatment for androgenetic alopecia, commonly known as pattern hair loss. Its active ingredient, minoxidil, works by prolonging the anagen (growth) phase of the hair cycle, increasing blood flow to follicles, and stimulating dormant hair follicles. This formulation is specifically indicated for men and has demonstrated significant efficacy in clinical trials for vertex baldness and frontal thinning when used consistently as directed. It represents a non-prescription, evidence-based option for individuals seeking to address progressive hair loss.

Features

  • Contains 5% minoxidil as the active pharmaceutical ingredient
  • Available in liquid solution or foam vehicle for topical application
  • Formulated with propylene glycol, ethanol, and water to enhance cutaneous absorption
  • Designed for once or twice-daily application depending on formulation and patient tolerance
  • Over-the-counter status allows for convenient access without prescription
  • Manufactured under strict pharmaceutical quality control standards

Benefits

  • Promotes visible hair regrowth in individuals with androgenetic alopecia
  • Slows the progression of pattern hair loss by extending the hair growth cycle
  • Increases hair density and coverage in affected scalp regions
  • Prevents further miniaturization of vulnerable hair follicles
  • Non-invasive treatment option compared to surgical interventions
  • Supported by decades of clinical research and real-world efficacy data

Common use

Rogaine 5 is primarily indicated for the treatment of male pattern hair loss (androgenetic alopecia) affecting the vertex (crown) and anterior mid-scalp areas. It is most effective in individuals with recent onset of hair loss (less than 5 years) and smaller areas of baldness. Patients typically begin to notice decreased hair shedding within 2 months of consistent use, with visible regrowth often apparent by 4 months. Maximum results are generally achieved after 12 months of continuous treatment. The product is not indicated for receding frontal hairline or complete baldness, and results are dependent on continued use—cessation of treatment typically leads to reversal of benefits within 3-4 months.

Dosage and direction

Apply 1 mL of the solution twice daily to the affected areas of the scalp, regardless of formulation type. For the foam formulation, half a capful is typically sufficient. The hair and scalp should be completely dry before application. Using the provided applicator, distribute the medication evenly across the affected area and gently massage into the scalp. Wash hands thoroughly after application. Do not shampoo for at least 4 hours after application. Do not exceed recommended dosage as increased application does not enhance efficacy and may increase risk of adverse effects.

Precautions

  • For external use only—avoid contact with eyes, mucous membranes, and broken skin
  • Not recommended for use by women except under specific physician guidance
  • May cause temporary increased hair shedding during the first 2-6 weeks of treatment
  • Cardiovascular effects including tachycardia or hypotension may occur, particularly in patients with pre-existing cardiac conditions
  • Monitor for signs of allergic contact dermatitis, especially to propylene glycol component
  • Avoid concurrent use of other topical scalp products unless approved by a healthcare provider
  • Discontinue use and consult a physician if no improvement is seen after 4 months of treatment

Contraindications

  • Hypersensitivity to minoxidil, propylene glycol, ethanol, or any component of the formulation
  • Patients with a history of pheochromocytoma
  • Individuals with unexplained scalp lesions, inflammation, or infection
  • Patients with a history of cardiovascular disease including arrhythmias, angina, or myocardial infarction
  • Concomitant use with guanethidine or similar vasodilators
  • Pregnancy and breastfeeding (due to systemic absorption potential)

Possible side effects

  • Local effects: pruritus, dryness, scaling, and irritation at application site (most common)
  • Dermatological: contact allergic dermatitis, erythema, and exacerbation of seborrheic dermatitis
  • Hypertrichosis: unwanted hair growth on adjacent areas such as forehead or temples
  • Cardiovascular: tachycardia, palpitations, dizziness, or syncope (rare with topical use)
  • Systemic: headache, fatigue, and fluid retention (typically with excessive application)
  • Temporary increased hair shedding during initial treatment phase

Drug interaction

While topical minoxidil has limited systemic absorption, potential interactions include:

  • Enhanced hypotensive effects when used with other vasodilators or antihypertensive medications
  • Possible potentiation of orthostatic hypotension with diuretics or alpha-blockers
  • Theoretical interaction with topical corticosteroids due to altered cutaneous absorption
  • No significant interactions with 5-alpha reductase inhibitors (finasteride, dutasteride)— often used concomitantly in hair loss regimens

Missed dose

If a dose is missed, apply as soon as remembered unless it is nearly time for the next scheduled application. Do not double the dose to make up for a missed application. Consistency is important for optimal results, but occasional missed doses are unlikely to significantly impact long-term efficacy. Maintain regular application schedule thereafter.

Overdose

Topical overdose may occur through excessive application or accidental ingestion. Symptoms may include severe hypotension, tachycardia, dizziness, syncope, and fluid retention. In case of accidental ingestion, seek immediate medical attention. Topical overdose should be managed by discontinuing use, washing the affected area, and symptomatic treatment if necessary. Systemic effects are unlikely with proper topical use but may occur with application to large areas or broken skin.

Storage

Store at room temperature (20-25°C or 68-77°F) in an upright position. Keep container tightly closed when not in use. Protect from light and excessive heat—do not store near radiators or in direct sunlight. The foam formulation is flammable—keep away from fire or flame until fully dried. Keep out of reach of children and pets. Do not use if solution changes color or develops precipitate. Discard 4 months after opening regardless of remaining content.

Disclaimer

This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Not all users will experience regrowth. For external use only. Discontinue use and consult a physician if irritation develops or if unexpected side effects occur. This information does not replace professional medical advice. Users should read all product labeling and instructions before use. Not evaluated by the FDA for safety and efficacy for uses other than androgenetic alopecia.

Reviews

Clinical studies demonstrate approximately 40% of men using 5% minoxidil experience moderate to dense regrowth after 48 weeks of treatment, compared to approximately 20% with placebo. Patient-reported outcomes indicate high satisfaction with maintenance of existing hair, though regrowth expectations should remain realistic. Dermatological clinical trials report approximately 5% of users discontinue due to local irritation, primarily from the solution vehicle. The foam formulation generally demonstrates improved tolerability with similar efficacy. Long-term users report sustained benefits with continuous use over multiple years, though maintenance rather than additional regrowth is typical after the first year.