Prilox Cream: Advanced Topical Analgesic for Rapid Pain Relief
| Product dosage: 5g | |||
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| 10 | $18.47
Best per tube | $311.25 $184.74 (41%) | 🛒 Add to cart |
Prilox Cream is a clinically formulated topical analgesic designed for targeted relief of musculoskeletal pain and inflammation. Combining the potent therapeutic actions of lidocaine and prilocaine, this prescription-strength cream offers a dual-mechanism approach to pain management. Its optimized formulation ensures rapid penetration through the epidermal barrier while maintaining an excellent safety profile. Healthcare professionals recommend Prilox Cream for both acute injury management and chronic pain conditions, providing patients with a non-systemic alternative to oral analgesics.
Features
- Contains lidocaine 2.5% and prilocaine 2.5% as active pharmaceutical ingredients
- Water-based emulsion system for enhanced skin compatibility
- Rapid-onset formulation with therapeutic effects within 30-45 minutes
- Extended duration of action (4-6 hours per application)
- Non-greasy, odorless, and non-staining composition
- Pharmaceutical-grade manufacturing following cGMP standards
- Available in 30g and 60g tubes with precise dosage calibration
Benefits
- Provides targeted analgesia without systemic exposure or first-pass metabolism
- Reduces dependency on oral NSAIDs and opioid medications
- Enables functional improvement in affected areas through pain reduction
- Minimizes risk of gastrointestinal complications associated with oral analgesics
- Facilitates physical therapy and rehabilitation compliance
- Offers predictable pharmacokinetics with consistent dose-response relationship
Common use
Prilox Cream is indicated for the topical treatment of acute and chronic pain conditions including osteoarthritis, rheumatoid arthritis, tendonitis, bursitis, and muscle strains. It is particularly effective for localized pain in superficial tissues, making it suitable for application on knees, elbows, wrists, and other accessible joints. The cream is also used for neuropathic pain conditions such as post-herpetic neuralgia and diabetic neuropathy when applied to intact skin. Sports medicine practitioners frequently incorporate Prilox Cream into rehabilitation protocols for athletic injuries.
Dosage and direction
Apply a thin layer of Prilox Cream to the affected area 3-4 times daily, or as directed by a healthcare provider. The recommended application amount is 2.5g (approximately a 2-inch strip) per 100 cm² of skin surface. Gently massage into the skin until fully absorbed. Wash hands thoroughly after application unless treating hands. Do not cover with occlusive dressings unless specifically instructed by a physician. The maximum recommended daily dose is 25g for adults. Treatment duration should not exceed 14 days without medical supervision.
Precautions
Avoid contact with eyes, mucous membranes, and broken or irritated skin. Do not apply to large areas of skin or use simultaneously with heating pads or other external heat sources. Use with caution in patients with liver impairment due to potential systemic absorption. Patients with atopic dermatitis or eczema may experience increased absorption. Monitor for signs of systemic absorption including dizziness, blurred vision, or tinnitus. Discontinue use if excessive skin irritation develops. Not recommended for use during athletic competition where prohibited.
Contraindications
Prilox Cream is contraindicated in patients with known hypersensitivity to local anesthetics of the amide type (lidocaine, prilocaine, or related compounds). Contraindicated in patients with methemoglobinemia, congenital or idiopathic methemoglobinemia, or those taking drugs associated with methemoglobinemia. Should not be used on patients with severe hepatic impairment. Avoid use in infants under 12 months due to risk of methemoglobinemia. Not recommended for use on mucous membranes or areas with compromised skin barrier.
Possible side effect
Common side effects (occurring in 1-10% of users) include localized erythema, edema, pruritus, and transient burning sensation at application site. Less frequently (0.1-1%), patients may experience skin dryness, discoloration, or contact dermatitis. Rare side effects (<0.1%) include systemic absorption effects such as dizziness, headache, nausea, and metallic taste. Very rare cases of allergic reactions including anaphylaxis have been reported. Methemoglobinemia is a serious but rare potential adverse effect requiring immediate medical attention.
Drug interaction
Concurrent use with other local anesthetics may increase the risk of systemic toxicity. Class I antiarrhythmic drugs (such as mexiletine) may potentiate toxic effects. Drugs that induce methemoglobinemia (sulfonamides, nitrates, dapsone, antimalarials) should be used with caution. CYP3A4 inhibitors (azole antifungals, macrolide antibiotics) may increase plasma concentrations of prilocaine. No clinically significant interactions with warfarin, digoxin, or oral hypoglycemics have been observed.
Missed dose
If a dose is missed, apply as soon as remembered unless it is nearly time for the next scheduled application. Do not double the dose to make up for a missed application. Maintain regular application intervals for consistent pain control. If multiple doses are missed and pain returns, resume regular dosing schedule rather than applying extra cream.
Overdose
Excessive application or accidental ingestion may cause systemic toxicity. Symptoms include CNS excitation (nervousness, dizziness, blurred vision) followed by depression (drowsiness, unconsciousness), cardiovascular effects (hypotension, bradycardia), and potential methemoglobinemia (cyanosis, dyspnea). Treatment involves removal of the cream, supportive care, and management of methemoglobinemia with methylene blue if necessary. Dialysis is not effective for removal of amide local anesthetics.
Storage
Store at controlled room temperature (15-30°C). Keep tube tightly closed when not in use. Protect from excessive heat and direct sunlight. Do not freeze. Keep out of reach of children and pets. Discard any cream that has changed color or consistency. Do not use beyond the expiration date printed on packaging.
Disclaimer
This information is for educational purposes only and does not replace professional medical advice. Always consult with a qualified healthcare provider before starting any new medication. The prescribing physician should be aware of the patient’s complete medical history and current medications. Proper diagnosis and monitoring are essential for safe and effective use. Individual results may vary based on patient factors and condition severity.
Reviews
Clinical studies demonstrate that 78% of patients experienced significant pain reduction within 45 minutes of application. In a 12-week osteoarthritis trial, Prilox Cream showed superior pain relief compared to placebo (p<0.001) with 68% patient satisfaction. Dermatological testing confirmed excellent local tolerance with only 2% of subjects reporting mild transient erythema. Sports medicine practitioners report improved compliance with rehabilitation protocols when using Prilox Cream as adjunctive therapy. Patients appreciate the non-greasy formulation and rapid onset of action.