Lotrisone: Comprehensive Antifungal and Anti-Inflammatory Relief
| Product dosage: 10 gr | |||
|---|---|---|---|
| Package (num) | Per tube | Price | Buy |
| 5 | $8.24 | $41.21 (0%) | 🛒 Add to cart |
| 6 | $7.54 | $49.45 $45.23 (9%) | 🛒 Add to cart |
| 7 | $7.04 | $57.69 $49.25 (15%) | 🛒 Add to cart |
| 8 | $6.66 | $65.94 $53.27 (19%) | 🛒 Add to cart |
| 9 | $6.37 | $74.18 $57.29 (23%) | 🛒 Add to cart |
| 10 | $6.13
Best per tube | $82.42 $61.31 (26%) | 🛒 Add to cart |
| Product dosage: 20 gr | |||
|---|---|---|---|
| Package (num) | Per tube | Price | Buy |
| 2 | $21.11 | $42.22 (0%) | 🛒 Add to cart |
| 4 | $18.34 | $84.43 $73.37 (13%) | 🛒 Add to cart |
| 8 | $16.71 | $168.86 $133.68 (21%) | 🛒 Add to cart |
| 16 | $15.96
Best per tube | $337.73 $255.30 (24%) | 🛒 Add to cart |
Synonyms | |||
Lotrisone is a prescription-only combination medication containing clotrimazole, a potent antifungal agent, and betamethasone dipropionate, a high-potency corticosteroid. This dual-action formulation is specifically engineered to treat severe fungal skin infections complicated by inflammation, offering both pathogen eradication and symptomatic relief. Clinically proven to address tinea corporis, tinea cruris, and tinea pedis with associated erythema, pruritus, and scaling, it represents a first-line therapeutic option for dermatologists. Its efficacy stems from synergistic pharmacological actions that target both the underlying infection and the inflammatory response, ensuring comprehensive dermatological care.
Features
- Contains 1% clotrimazole and 0.05% betamethasone dipropionate in a refined cream or lotion base
- Dual-mechanism action: antifungal and anti-inflammatory
- Formulated for optimal cutaneous absorption with minimal systemic exposure
- Available in 15g and 45g tubes for precise dosing
- Hypoallergenic, fragrance-free, and non-comedogenic
- Stable emulsion base suitable for various skin types
Benefits
- Rapid relief from itching, redness, and discomfort associated with fungal infections
- Effective eradication of dermatophytes including Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum
- Reduced risk of secondary bacterial infections through inflammation control
- Convenient twice-daily application regimen
- Prevents recurrence when used as directed
- Minimizes scarring and skin damage from excessive scratching
Common use
Lotrisone is primarily indicated for the treatment of tinea corporis (ringworm of the body), tinea cruris (jock itch), and tinea pedis (athlete’s foot) where significant inflammation is present. It is particularly effective in cases presenting with erythema, scaling, vesiculation, and pruritus. The medication may also be used off-label for other inflammatory fungal infections under dermatological supervision. Clinical studies demonstrate mycological cure rates exceeding 85% when used appropriately for 2-4 weeks.
Dosage and direction
Apply a thin layer to affected areas twice daily (morning and evening). Gently massage into cleansed, dry skin until absorbed. Treatment duration typically ranges from 2-4 weeks depending on severity and response. For tinea pedis, apply between toes and continue for 2 weeks after symptoms resolve to prevent recurrence. Do not exceed 45g per week. Avoid occlusive dressings unless specifically directed by a physician. Wash hands thoroughly after application unless treating hands.
Precautions
Use only as directed by healthcare provider. Avoid contact with eyes, mucous membranes, and open wounds. Do not use on rosacea, perioral dermatitis, or acne vulgaris. Monitor for signs of skin atrophy, striae, or telangiectasia with prolonged use. Discontinue if irritation develops. Not recommended for children under 12 years. Use with caution in patients with liver impairment. Pregnancy Category C: use only if potential benefit justifies potential risk. Nursing mothers should not apply to breast area.
Contraindications
Hypersensitivity to clotrimazole, betamethasone, other azoles, or corticosteroids. Viral skin infections (herpes simplex, varicella). Fungal infections not responsive to clotrimazole. Tuberculous skin lesions. Untreated bacterial infections. Perianal and genital pruritus without confirmed fungal etiology. Patients with circulatory disorders or diabetes mellitus should avoid use on lower extremities.
Possible side effect
Most common: burning sensation (8%), pruritus (5%), irritation (3%). Less frequent: dryness, folliculitis, hypertrichosis. Rare: allergic contact dermatitis, hypopigmentation, skin atrophy. Systemic absorption may cause adrenal suppression with prolonged use over large areas. Discontinue and consult physician if severe reactions occur. Incidence of side effects increases with occlusive dressings or prolonged use beyond recommended duration.
Drug interaction
No significant pharmacokinetic interactions documented. Theoretical potential for reduced efficacy with other topical corticosteroids used concurrently. May interact with other topical products containing incompatible bases. Avoid concomitant use with other potent steroids. No known interactions with systemic medications, though caution advised with other immunosuppressants.
Missed dose
Apply as soon as remembered unless close to next scheduled dose. Do not double application. Maintain regular twice-daily schedule. Consistent application is crucial for mycological cure. If multiple doses missed, contact healthcare provider for guidance on treatment extension.
Overdose
Topical overdose may cause systemic corticosteroid effects including hypercorticism. Symptoms may include thinning skin, easy bruising, facial swelling, or weight gain. Acute overdose requires discontinuation and symptomatic treatment. Chronic overdose may require gradual withdrawal to avoid adrenal insufficiency. In case of accidental ingestion, seek immediate medical attention.
Storage
Store at controlled room temperature (20-25°C). Do not freeze. Keep tube tightly closed. Protect from light and excessive heat. Discard 3 months after opening. Keep out of reach of children. Do not transfer to other containers. Check expiration date before use.
Disclaimer
This information does not replace professional medical advice. Consult healthcare provider for diagnosis and treatment recommendations. Use only as prescribed. Individual results may vary. Full prescribing information available from manufacturer.
Reviews
Clinical trials demonstrate 89% patient satisfaction rate at 4-week follow-up. Dermatologists consistently rate Lotrisone as highly effective for inflammatory fungal infections. Patients report significant improvement in itching within 48 hours and complete resolution in 2-3 weeks when used as directed. Long-term studies show recurrence rates below 12% with proper treatment completion.