Ferrous: Advanced Iron Supplement for Optimal Hemoglobin Support

Ferrous represents a clinically-formulated iron supplement designed to address iron deficiency and support robust erythropoiesis. Developed for patients with confirmed iron-deficiency anemia or those at risk due to physiological or pathological conditions, this product offers high elemental iron bioavailability with minimized gastrointestinal distress. Its targeted release mechanism ensures efficient absorption in the duodenum and proximal jejunum, making it a first-line option in hematological supplementation protocols under medical supervision.

Features

  • Contains 65 mg of elemental iron as ferrous sulfate in delayed-release capsules
  • Includes 100 mg of ascorbic acid to enhance iron absorption
  • Delayed-release formulation to reduce gastric irritation
  • Vegan-friendly capsule shell, free from gluten and major allergens
  • Manufactured in a cGMP-certified facility with third-party purity verification
  • Packaged in HDPE bottles with oxygen-absorbing desiccant for stability

Benefits

  • Significantly increases hemoglobin and hematocrit levels within 4–8 weeks of consistent use
  • Reduces symptoms of iron-deficiency anemia such as fatigue, pallor, and exertional dyspnea
  • Supports cognitive function and immune competency through adequate iron-dependent enzyme systems
  • Minimizes common side effects like nausea and constipation through targeted release technology
  • Provides a cost-effective, non-invasive alternative to intravenous iron therapy in appropriate cases
  • Enables better adherence through once-daily dosing and improved gastrointestinal tolerance

Common use

Ferrous is indicated for the treatment of iron-deficiency anemia in adults and adolescents over 12 years of age. It is commonly prescribed following confirmed laboratory diagnosis (serum ferritin <30 ng/mL, low MCV, elevated TIBC) in cases including chronic blood loss (e.g., menorrhagia, GI bleeding), pregnancy, malnutrition, malabsorption syndromes (e.g., celiac disease, post-gastrectomy), and in patients with chronic kidney disease not on erythropoietin therapy. Off-label use may include prophylaxis in high-risk populations such as endurance athletes or vegetarians with borderline iron stores, though laboratory monitoring is recommended.

Dosage and direction

The standard therapeutic dosage for adults and adolescents is one capsule (65 mg elemental iron) daily, taken on an empty stomach at least 1 hour before or 2 hours after meals. If gastric discomfort occurs, administration with a small amount of food is acceptable though absorption may be reduced. Swallow whole with a full glass of water; do not crush or chew. For optimal absorption, avoid concomitant consumption with dairy products, calcium supplements, antacids, or tea within 2 hours of dosing. Treatment duration typically ranges from 3 to 6 months, followed by re-assessment of iron stores. Prophylactic dosing may be reduced to one capsule every other day as directed by a healthcare provider.

Precautions

Periodic monitoring of hemoglobin, ferritin, and complete blood count is recommended every 4–6 weeks during treatment. Use with caution in patients with inflammatory bowel disease, peptic ulcer disease, or diverticulosis. May cause darkening of stools—this is harmless but should be distinguished from melena. Not recommended for patients with hemochromatosis, hemosiderosis, or other iron overload disorders. Keep out of reach of children; iron overdose is a leading cause of fatal pediatric poisoning. Pregnant individuals should use only under medical supervision; iron requirements increase during pregnancy but excess iron may pose oxidative stress risks.

Contraindications

Absolute contraindications include known hypersensitivity to any component, hemochromatosis, hemosiderosis, hemolytic anemia, and repeated blood transfusions. Relative contraindications include active peptic ulcer disease, regional enteritis, ulcerative colitis, and severe hepatic impairment. Not recommended for use in patients with anemia not attributed to iron deficiency (e.g., thalassemia, sideroblastic anemia) without thorough diagnostic workup.

Possible side effect

Common (≥1/100): Gastrointestinal discomfort, nausea, epigastric pain, constipation, dark stools. Less common (≥1/1000): Diarrhea, heartburn, transient tooth staining. Rare (<1/1000): Allergic reactions, urticaria, exacerbation of existing gastrointestinal conditions. Very rare: Iron overload in susceptible individuals with prolonged unsupervised use. Most side effects are dose-dependent and may diminish with continued use or dose adjustment.

Drug interaction

Iron absorption is significantly reduced when taken with tetracyclines, quinolones, bisphosphonates, levothyroxine, penicillamine, and mycophenolate—separate administration by at least 4 hours. Antacids, H2-receptor antagonists, and proton-pump inhibitors may decrease iron absorption. Cholestyramine and mineral oils may reduce efficacy. Ascorbic acid component may increase aluminum absorption from phosphate binders in renal impairment. May reduce absorption of methyldopa, levodopa, and carbidopa.

Missed dose

If a dose is missed, take it as soon as remembered unless it is nearly time for the next dose. Do not double the dose to make up for a missed one. Consistency in dosing is important for effective repletion but occasional missed doses are unlikely to significantly impact long-term outcomes given iron’s cumulative storage mechanism.

Overdose

Acute iron overdose (>20 mg/kg elemental iron) is a medical emergency requiring immediate intervention. Early symptoms (within 6 hours) include vomiting (sometimes bloody), diarrhea, abdominal pain, lethargy, and metabolic acidosis. Later stages (12–48 hours) may involve shock, coagulopathy, hepatic necrosis, and gastrointestinal scarring. Chronic overdose may lead to hemosiderosis. Treatment includes gastric lavage (if within 1 hour), whole bowel irrigation, and chelation therapy with deferoxamine in severe cases. Serum iron levels and clinical status guide management.

Storage

Store at room temperature (15–30°C) in the original container with tight closure. Protect from moisture, light, and heat. Do not transfer to alternative containers. Keep bottle desiccant intact. Discard any capsules showing signs of moisture damage, discoloration, or odor. Shelf life: 36 months from manufacture date. Do not use after expiration date printed on packaging.

Disclaimer

This product is intended for use under medical supervision. It is not intended to diagnose, treat, cure, or prevent any disease without professional guidance. The information provided does not replace consultation with a qualified healthcare provider. Individual results may vary based on physiological factors, adherence, and underlying health conditions. Always follow your healthcare provider’s instructions regarding dosage, duration, and monitoring.

Reviews

“As a hematologist, I’ve prescribed Ferrous to over 200 patients with iron-deficiency anemia. The delayed-release formulation markedly improves compliance—I’ve observed a 40% reduction in discontinuation due to GI side effects compared to conventional iron salts. Hemoglobin response rates are consistent and predictable.” — Dr. Eleanor Vance, MD

“After years of struggling with iron deficiency due to celiac disease, I finally found a supplement that doesn’t exacerbate my gastrointestinal symptoms. My ferritin levels normalized within three months, and my energy levels have improved significantly.” — Maria J., verified patient

“The inclusion of ascorbic acid is a thoughtful touch—it eliminates the need for separate vitamin C supplementation and simplifies the regimen for my elderly patients.” — Pharmacist David Chen, RPh

“I use Ferrous prophylactically during marathon training seasons. Regular monitoring shows I maintain low-normal ferritin levels without needing to interrupt training due to deficiency symptoms.” — Marcus R., endurance athlete

“As an OB/GYN, I appreciate having a well-tolerated iron option for my second- and third-trimester patients. The once-daily dosing is manageable even for those with severe nausea.” — Dr. Sofia Rivera, OB/GYN