Doxt SL: Advanced Dual-Action Therapy for Respiratory Relief
| Product dosage: 100mg | |||
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Doxt SL is a prescription medication combining Doxycycline and Serratiopeptidase, designed to address complex respiratory and inflammatory conditions with precision. This fixed-dose combination leverages the antibacterial potency of doxycycline—a broad-spectrum tetracycline antibiotic—with the potent proteolytic and anti-inflammatory action of serratiopeptidase. Clinically formulated for enhanced bioavailability and targeted efficacy, Doxt SL is indicated for conditions where infection coexists with significant inflammation and tissue edema. Its dual mechanism ensures comprehensive management, reducing both microbial load and associated inflammatory responses, thereby accelerating recovery and improving patient outcomes.
Features
- Contains Doxycycline 100 mg and Serratiopeptidase 15 mg per tablet
- Broad-spectrum antibacterial coverage against Gram-positive and Gram-negative organisms
- Potent anti-inflammatory, fibrinolytic, and edema-reducing properties
- Film-coated tablets for easier swallowing and gastric tolerance
- Stable at room temperature with a standard shelf life of 24 months
Benefits
- Effectively eradicates bacterial pathogens responsible for respiratory and soft tissue infections
- Reduces swelling, pain, and inflammation through enzymatic breakdown of inflammatory mediators
- Accelerates tissue repair and resolution of symptoms such as dyspnea and purulent discharge
- Minimizes risk of secondary infection and chronicity through complete antimicrobial action
- Enhances patient compliance with a convenient twice-daily dosing regimen
- Supports faster return to normal activity and reduced antibiotic course duration
Common use
Doxt SL is commonly prescribed for acute and chronic bronchitis, community-acquired pneumonia, sinusitis, and tonsillitis where bacterial infection is confirmed or strongly suspected. It is also used in the management of postoperative inflammation, wound infections, and soft tissue abscesses. The combination is particularly beneficial in cases with pronounced edema, viscous secretions, or delayed recovery, where anti-inflammatory support is necessary alongside antimicrobial therapy.
Dosage and direction
The standard adult dosage is one tablet of Doxt SL twice daily, taken after meals to minimize gastrointestinal discomfort. Tablets should be swallowed whole with a full glass of water; do not crush or chew. The usual treatment duration ranges from 7 to 14 days, depending on severity and clinical response. In cases of severe infection or slow resolution, therapy may be extended under medical supervision. Dosage adjustment may be required in patients with renal impairment.
Precautions
Avoid prolonged exposure to sunlight or UV rays, as doxycycline can cause photosensitivity reactions. Use with caution in patients with a history of gastrointestinal disease, particularly colitis. Serratiopeptidase may increase the risk of bleeding; exercise caution in patients with coagulation disorders or those taking anticoagulants. Do not use beyond the expiration date. Not recommended during pregnancy or lactation unless clearly needed.
Contraindications
Doxt SL is contraindicated in patients with known hypersensitivity to doxycycline, other tetracyclines, serratiopeptidase, or any component of the formulation. It is also contraindicated in children under 8 years of age due to the risk of tooth discoloration and enamel hypoplasia associated with tetracycline use. Avoid use in patients with severe hepatic impairment or porphyria.
Possible side effects
Common side effects may include nausea, vomiting, diarrhea, or abdominal pain. Less frequently, skin rash, photosensitivity, dizziness, or headache may occur. Serratiopeptidase may rarely cause gastrointestinal bleeding, allergic reactions, or bronchospasm. Discontinue use and seek medical attention if severe diarrhea, signs of an allergic reaction (e.g., swelling, difficulty breathing), or unusual bleeding occur.
Drug interaction
Doxt SL may interact with antacids, iron preparations, and calcium supplements, reducing doxycycline absorption. Concurrent use with warfarin or other anticoagulants may potentiate anticoagulant effects. Barbiturates, carbamazepine, and phenytoin may reduce doxycycline levels. Avoid concomitant use with retinoids or penicillin antibiotics. Serratiopeptidase may enhance the effects of antiplatelet and thrombolytic agents.
Missed dose
If a dose is missed, take it as soon as remembered unless it is almost time for the next dose. Do not double the dose to make up for a missed one. Maintain the regular dosing schedule to ensure consistent therapeutic levels.
Overdose
Symptoms of overdose may include severe nausea, vomiting, diarrhea, or dizziness. In case of suspected overdose, seek immediate medical attention. Treatment is supportive; gastric lavage may be considered if ingestion was recent. Hemodialysis is not effective for removing doxycycline or serratiopeptidase.
Storage
Store below 30°C (86°F), in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date printed on the packaging.
Disclaimer
This information is intended for medical professionals and should not replace personalized medical advice. Always consult a healthcare provider for diagnosis, treatment recommendations, and dosing tailored to individual patient needs. Use only as prescribed.
Reviews
“Highly effective in stubborn cases of bacterial sinusitis with significant edema. Patients report noticeable improvement within 48–72 hours.” — Dr. A. Sharma, Pulmonologist
“Combination therapy with Doxt SL has reduced the need for additional NSAIDs in my practice, especially in postoperative patients.” — Dr. L. Lopez, Surgeon
“Excellent tolerability and compliance. The twice-daily dosing is convenient for working adults.” — Clinical Nurse Specialist, Respiratory Ward