Cepmox: Advanced Broad-Spectrum Antibiotic Therapy
| Product dosage: 250mg | |||
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Cepmox is a next-generation cephalosporin antibiotic formulated for potent, broad-spectrum bacterial eradication. It combines amoxicillin with a beta-lactamase inhibitor to overcome resistant pathogens, ensuring reliable coverage in both community and hospital-acquired infections. Clinically validated for efficacy and safety, Cepmox offers healthcare professionals a trusted option for managing moderate to severe bacterial infections with optimized pharmacokinetics and minimal resistance development.
Features
- Contains amoxicillin 500mg and clavulanic acid 125mg per tablet
- Extended-spectrum activity against Gram-positive and Gram-negative bacteria
- Beta-lactamase inhibitor enhances stability against enzyme-mediated resistance
- Bioavailability of over 90% with rapid serum concentration peaks
- Twice-daily dosing regimen supports patient adherence
- Manufactured under cGMP standards with batch-to-batch consistency
Benefits
- Effectively eradicates multidrug-resistant bacterial strains
- Reduces risk of treatment failure in empirically managed infections
- Minimizes hospitalization duration through rapid clinical response
- Low incidence of gastrointestinal side effects due to optimized formulation
- Suitable for adult and pediatric populations (weight-adjusted dosing)
- Prevents recurrence in chronic or recurrent infection cases
Common use
Cepmox is indicated for the treatment of bacterial infections including community-acquired pneumonia, acute bacterial sinusitis, otitis media, skin and soft tissue infections, urinary tract infections, and intra-abdominal infections. It is also used for prophylactic coverage in surgical procedures involving the gastrointestinal tract. Off-label use may include dental infections and bite wounds, following susceptibility testing.
Dosage and direction
Adults and children ≥40 kg:
One tablet (500mg/125mg) every 12 hours for 7–14 days, depending on infection severity.
Children <40 kg:
20–40 mg/kg/day (based on amoxicillin component) divided every 12 hours.
Take with food to enhance absorption and reduce gastrointestinal upset. Complete the full course even if symptoms improve earlier. For severe infections or those caused by less susceptible organisms, dosage may be increased to one tablet every 8 hours.
Precautions
- Use with caution in patients with hepatic impairment; monitor liver enzymes periodically
- Assess renal function before initiation and adjust dose if creatinine clearance is <30 mL/min
- May cause antibiotic-associated colitis; discontinue if diarrhea develops
- Not recommended during pregnancy unless potential benefit justifies potential risk
- Use in lactating women only if clearly needed; amoxicillin excretes in breast milk
- Prolonged use may result in fungal or bacterial superinfection
Contraindications
- History of hypersensitivity to beta-lactam antibiotics (penicillins, cephalosporins)
- Previous episodes of Cepmox-associated jaundice or hepatic dysfunction
- Patients with phenylketonuria (tablets contain phenylalanine)
- Concomitant use with disulfiram or alcohol-containing products
Possible side effect
Common (≥1%): diarrhea, nausea, vomiting, abdominal pain, skin rash.
Less common (<1%): vaginal candidiasis, headache, dizziness, transient elevations in liver enzymes.
Rare: pseudomembranous colitis, hepatitis, eosinophilia, Stevens-Johnson syndrome.
Discontinue immediately if signs of hypersensitivity reaction occur.
Drug interaction
- Probenecid decreases renal tubular secretion of amoxicillin, increasing serum concentration
- Concurrent use with oral anticoagulants may enhance anticoagulant effect
- Reduces efficacy of oral contraceptives; advise alternative contraception during therapy
- Allopurinol increases incidence of skin rash
- May alter intestinal flora, reducing efficacy of estrogen-containing therapies
Missed dose
Take the missed dose as soon as remembered unless it is almost time for the next dose. Do not double the dose to catch up. Resume the regular dosing schedule. Consistent dosing is critical to maintain therapeutic blood levels.
Overdose
Symptoms may include nausea, vomiting, diarrhea, electrolyte imbalance, or crystalline. Gastrointestinal symptoms are managed supportively. Hemodialysis can remove both amoxicillin and clavulanic acid. Maintain hydration and electrolyte balance. Contact poison control or seek emergency medical attention.
Storage
Store at room temperature (15–30°C) in the original container. Protect from light and moisture. Keep out of reach of children. Do not use after the expiration date printed on the packaging. Do not transfer to alternative containers.
Disclaimer
This information is intended for healthcare professionals. Always confirm susceptibility testing before prescribing. Dosage and administration must be individualized based on patient factors, infection type, and local resistance patterns. Not all uses or interactions are listed; consult full prescribing information before use.
Reviews
“Cepmox has become my first-line choice for resistant respiratory infections. The twice-daily dosing improves compliance, and I’ve observed faster symptom resolution compared to other agents.” — Dr. Elena Rostova, Infectious Disease Specialist
“Effective in pediatric otitis media cases where first-line antibiotics failed. Weight-based dosing is straightforward, and the suspension formulation is well-accepted.” — Dr. Mark Higgins, Pediatrician
“Notable reduction in postoperative infection rates in colorectal surgery when used for prophylaxis. Well-tolerated with minimal disruption to gut flora.” — Dr. Sofia Rivera, Surgical Department
“A reliable option for diabetic foot infections. The spectrum covers most common pathogens, and the low resistance profile makes it particularly valuable.” — Dr. Ben Carter, Podiatrist