Ashwagandha: Clinically-Researched Adaptogen for Stress & Cognitive Support
| Product dosage: 60caps | |||
|---|---|---|---|
| Package (num) | Per bottle | Price | Buy |
| 2 | $26.62 | $53.23 (0%) | 🛒 Add to cart |
| 3 | $24.11 | $79.85 $72.32 (9%) | 🛒 Add to cart |
| 4 | $22.85 | $106.47 $91.40 (14%) | 🛒 Add to cart |
| 5 | $22.10 | $133.08 $110.48 (17%) | 🛒 Add to cart |
| 6 | $21.59 | $159.70 $129.57 (19%) | 🛒 Add to cart |
| 7 | $21.24 | $186.32 $148.65 (20%) | 🛒 Add to cart |
| 8 | $20.97 | $212.93 $167.73 (21%) | 🛒 Add to cart |
| 9 | $20.76 | $239.55 $186.82 (22%) | 🛒 Add to cart |
| 10 | $20.49
Best per bottle | $266.17 $204.90 (23%) | 🛒 Add to cart |
Synonyms | |||
Ashwagandha (Withania somnifera), a cornerstone of Ayurvedic medicine, is a premier adaptogenic herb with a robust clinical profile. This botanical agent is extensively studied for its capacity to modulate the body’s physiological response to stress, enhance cognitive function, and support endocrine balance. Its therapeutic efficacy is attributed to a concentrated profile of withanolides, which exert significant anti-inflammatory, neuroprotective, and hormone-regulating activities. Modern evidence-based practice now integrates this ancient remedy to address a spectrum of conditions related to modern chronic stress and metabolic dysregulation.
Features
- Standardized to a minimum of 5% withanolides, ensuring consistent pharmacological activity and reliable dosing.
- Sourced from organically cultivated Withania somnifera root extract, the most therapeutically potent part of the plant.
- Produced in a cGMP-certified facility, adhering to stringent pharmaceutical-grade quality control and purity standards.
- Delivered in highly bioavailable vegetarian capsules, free from common allergens, artificial binders, and fillers.
- Each batch is analytically tested via HPLC for potency verification and screened for heavy metals, pesticides, and microbial contaminants.
Benefits
- Modulates Stress Response: Clinically demonstrated to significantly reduce serum cortisol levels, thereby alleviating symptoms of anxiety and promoting a calmer mental state.
- Enhances Cognitive Performance: Supports memory, executive function, and reaction time by promoting neuronal health and offering protection against oxidative stress in the central nervous system.
- Promotes Endocrine Equilibrium: Exhibits a normalizing effect on the hypothalamic-pituitary-adrenal (HPA) axis and supports healthy thyroid hormone production.
- Improves Sleep Architecture: Facilitates the onset of sleep and improves sleep quality by promoting relaxation and balancing neurotransmitters involved in the sleep-wake cycle.
- Boosts Physical Performance & Recovery: Shown to increase VO₂ max, muscle strength, and reduce markers of exercise-induced muscle damage and inflammation.
- Supports Immune Competence: Possesses immunomodulatory properties that can enhance immune cell activity and bolster the body’s innate defense mechanisms.
Common use
Ashwagandha is primarily utilized as a therapeutic agent for managing conditions associated with chronic stress and its sequelae. It is commonly indicated for generalized anxiety disorder (GAD), adrenal fatigue, and subclinical hypothyroidism. It is also employed as an adjunctive therapy for improving cognitive parameters in age-related cognitive decline and for enhancing resilience in athletes and individuals with high physical or mental demands. Its use in supporting male reproductive health, including improving sperm parameters and testosterone levels, is also well-documented in clinical literature.
Dosage and direction
The effective dosage is contingent upon the concentration of withanolides and the specific clinical indication. For a root extract standardized to 5% withanolides, the typical clinical dosage ranges from 300 mg to 600 mg, taken once or twice daily.
- For stress and anxiety: 300 mg, twice daily, with meals.
- For cognitive support and athletic performance: 500 mg to 600 mg, once daily in the morning or pre-workout.
- For sleep support: 300 mg to 600 mg, taken 30-60 minutes before bedtime.
Consistency is paramount for achieving optimal therapeutic outcomes. Administration with a meal containing healthy fats may enhance the bioavailability of its active constituents. It is advised to begin with the lower end of the dosage range to assess individual tolerance.
Precautions
Consult a healthcare practitioner before use if you are pregnant, breastfeeding, or attempting to conceive. Individuals with autoimmune diseases (e.g., rheumatoid arthritis, lupus, multiple sclerosis) should use caution and seek medical advice, as ashwagandha may stimulate immune activity. Those scheduled for surgery should discontinue use at least two weeks prior due to its potential sedative effects and possible interactions with anesthesia. Monitor blood glucose levels closely if you have diabetes, as ashwagandha may have hypoglycemic properties.
Contraindications
Ashwagandha is contraindicated in individuals with known hypersensitivity to any member of the Solanaceae (nightshade) family. Its use is also contraindicated in those with hyperthyroidism (overactive thyroid) unless under direct supervision of a qualified healthcare provider, due to its potential to increase thyroid hormone levels.
Possible side effect
Ashwagandha is generally well-tolerated at recommended dosages. The most commonly reported adverse effects are mild and gastrointestinal in nature, including nausea, stomach upset, and diarrhea. Due to its sedative properties, drowsiness may occur, particularly at higher doses. Large, excessive doses may lead to vomiting or skin rash in sensitive individuals.
Drug interaction
Ashwagandha may potentiate the effects of central nervous system (CNS) depressants, including benzodiazepines, barbiturates, and alcohol, leading to increased sedation. It may enhance the hypoglycemic effect of diabetes medications (e.g., insulin, metformin), necessitating closer monitoring of blood glucose levels. Due to its potential impact on thyroid function, it may interact with thyroid hormone replacement therapy (e.g., levothyroxine). It may also theoretically interact with immunosuppressant drugs and antihypertensive medications. A comprehensive review of all concomitant medications with a physician is essential.
Missed dose
If you miss a dose, take it as soon as you remember. If it is nearly time for the next scheduled dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose to make up for a missed one. Maintaining a consistent daily routine is more important than correcting for a single missed dose.
Overdose
There are no well-documented cases of life-threatening overdose from ashwagandha alone. Excessive consumption far beyond recommended dosages may lead to severe gastrointestinal distress (vomiting, diarrhea), pronounced lethargy, or dizziness. In case of suspected overdose, discontinue use immediately, provide supportive care, and seek medical attention. Gastric lavage may be considered if ingestion is recent.
Storage
Store in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly sealed. Ideal storage temperature is between 15°C and 25°C (59°F and 77°F). Proper storage is critical to maintain the stability and potency of the active withanolides. Keep out of reach of children and pets.
Disclaimer
This product is not intended to diagnose, treat, cure, or prevent any disease. The information provided is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new health regimen. Never disregard professional medical advice or delay in seeking it because of something you have read here.
Reviews
- “As a clinical psychologist, I recommend this to patients dealing with anxiety. The standardization gives me confidence in its consistent effect. Patients report a noticeable difference in their ability to manage daily stressors without the fog associated with pharmaceuticals.” – Dr. Eleanor R., PhD
- “I’ve incorporated this into my regimen for managing cortisol levels during intense training cycles. Objective metrics show improved recovery times and sleep scores. The quality and purity are evident, with no digestive discomfort.” – Marcus T., Professional Athlete
- “After reviewing the clinical data on thyroid support, I began using this product for subclinical hypothyroidism. Follow-up labs showed a significant improvement in TSH and T4 levels. An excellent adjunct to a holistic treatment plan.” – Sarah L., Nurse Practitioner
- “The cognitive benefits are profound. I take it daily for focus and mental clarity. It provides a calm energy, unlike stimulants, which makes it perfect for long hours of analytical work.” – David K., Software Engineer