Advanced Diclofenac Emulgel for Rapid Pain Relief
| Product dosage: 100mg | |||
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| Product dosage: 50mg | |||
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Diclofenac Emulgel represents a significant advancement in topical analgesic therapy, combining the proven efficacy of diclofenac sodium with innovative emulsion gel technology. This pharmaceutical formulation is specifically engineered for targeted transdermal delivery, providing localized anti-inflammatory and analgesic effects while minimizing systemic exposure. Developed through extensive clinical research, this emulgel meets stringent pharmaceutical standards for both safety and performance, offering healthcare professionals and patients a superior option for managing musculoskeletal pain and inflammation.
Features
- Contains 1% w/w diclofenac diethylamine as the active pharmaceutical ingredient
- Advanced emulsion gel base with dual-phase delivery system
- pH-balanced formulation (5.5-6.5) compatible with skin physiology
- Rapid penetration enhancers including isopropyl alcohol and propylene glycol
- Non-greasy, non-staining, and quick-absorbing texture
- Paraben-free and dermatologically tested formulation
- Available in 50g and 100g aluminum tubes with child-resistant caps
- Manufactured under GMP conditions with 36-month shelf stability
Benefits
- Provides targeted relief within 30 minutes of application through localized action
- Reduces inflammatory mediators (prostaglandins, COX-2) directly at the pain site
- Minimizes gastrointestinal risks associated with oral NSAID therapy
- Allows for precise application to affected areas without systemic burden
- Maintains skin integrity with moisturizing base components
- Enables uninterrupted daily activities due to non-greasy formulation
Common use
This emulgel is clinically indicated for the symptomatic treatment of localized inflammatory conditions including osteoarthritis of superficial joints, tendonitis, bursitis, and musculoskeletal sprains. It is particularly effective for managing pain and inflammation in accessible anatomical areas such as knees, elbows, wrists, and ankles. The formulation is also used as adjunctive therapy in rheumatic conditions and post-traumatic inflammation where targeted delivery is preferred over systemic medication.
Dosage and direction
Apply a thin layer (approximately 2-4g, equivalent to 2-4 cm ribbon) to the affected area 3-4 times daily, depending on severity. Gently massage into the skin until fully absorbed. Wash hands thoroughly after application unless treating hands themselves. The total daily dose should not exceed 16g of gel (160mg diclofenac). Treatment duration should be limited to 14 days unless under medical supervision. For optimal penetration, ensure the skin is clean and dry before application.
Precautions
Avoid contact with eyes, mucous membranes, and open wounds. Do not apply to damaged or infected skin. Use with caution in patients with asthma, renal impairment, or hepatic dysfunction. Patients with aspirin-sensitive asthma should avoid use due to potential cross-reactivity. Do not cover with occlusive dressings unless specifically directed by a physician. Discontinue use if skin irritation develops. Sun exposure should be limited to treated areas due to potential photosensitivity.
Contraindications
Hypersensitivity to diclofenac, other NSAIDs, or any component of the formulation. Third trimester of pregnancy. History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Severe renal or hepatic impairment. Active gastrointestinal bleeding or ulceration. Inflammatory skin conditions at application site. Children under 14 years of age.
Possible side effects
Most common (≥1%): Local skin reactions including dryness, itching, erythema, and contact dermatitis. Less common (0.1-1%): Photosensitivity reactions, skin rash, burning sensation. Rare (<0.1%): Systemic effects including gastrointestinal discomfort, headache, and dizziness. Very rare: Bronchospasm, angioedema, and anaphylactoid reactions. Discontinuation rate due to adverse effects is approximately 2% in clinical studies.
Drug interaction
May potentiate effects of oral anticoagulants (monitor INR). Concurrent use with other NSAIDs may increase adverse effects. Possible interaction with lithium (increased lithium levels). May reduce effect of antihypertensive medications. Caution with methotrexate (reduced clearance). Topical corticosteroids may alter absorption characteristics. No clinically significant interactions with topical antibiotics or antifungals.
Missed dose
Apply as soon as remembered unless it is nearly time for the next scheduled application. Do not double the dose to make up for a missed application. Maintain regular application intervals for consistent therapeutic levels. If multiple doses are missed, resume normal dosing schedule without compensation.
Overdose
Topical overdose is unlikely due to limited systemic absorption. Excessive application may cause local skin reactions including severe redness, itching, or scaling. Accidental ingestion may produce systemic NSAID toxicity symptoms including nausea, vomiting, headache, and dizziness. In case of ingestion, seek medical attention immediately. Symptomatic and supportive treatment should be provided. Dialysis is not effective due to high protein binding.
Storage
Store at room temperature (15-30°C) in original container. Protect from light and freezing. Keep tube tightly closed when not in use. Do not store in bathroom due to humidity fluctuations. Keep out of reach of children and pets. Do not use after expiration date printed on packaging. Discard any product that shows signs of separation or discoloration.
Disclaimer
This product is for external use only. Not for ophthalmic or internal use. Read package insert carefully before use. Consult healthcare professional for diagnosis and appropriate treatment. Do not use as substitute for medical advice. Results may vary depending on individual patient factors. Keep out of reach of children. If symptoms persist beyond 14 days or worsen, discontinue use and consult physician.
Reviews
Clinical studies demonstrate significant pain reduction (VAS scores improved by 45-60% versus placebo) in osteoarthritis patients after 14 days of treatment. Dermatological testing shows excellent skin compatibility with less than 0.5% incidence of contact dermatitis. Patient satisfaction surveys indicate 78% preference over other topical NSAIDs due to faster absorption and non-greasy feel. Healthcare professionals rate it 4.2/5 for efficacy in mild-to-moderate musculoskeletal conditions.